East Asia, South Asia

Thursday 10 June 2010 · 0 comments

    East Asia


China

China’s first AIDS case was reported in Beijing in 1985. Today, an estimated 700,000 people in China are living with HIV (0.1% of the adult population), but it’s feared that this number will increase dramatically in future years, as HIV spreads from the groups most at risk to the general population.1 The most frequent modes of HIV transmission have been injecting drug use in southern and western China and unsafe practices among paid blood donors. Heterosexually transmitted HIV is occurring primarily in the eastern provinces of China, fuelled by an increasing commercial sex trade and by the large number of migrants moving to these provinces in search of labour. HIV has been identified in some urban areas among men who have sex with men but this population is stigmatized and is difficult to survey.
In 2007 an estimated 39,000 people died from AIDS in China.2

Country profiles - South East Asia

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Cambodia

Cambodia’s HIV epidemic can be traced back to 1991. After an initial rapid increase, HIV infection levels declined after the late 1990s and by 2003 HIV prevalence was estimated at 1.2%.1 Results published in 2009 from the first national population-based survey estimated HIV prevalence at 0.6%.2 It’s believed that interventions with sex workers, carried out by the government and non-governmental organisations (NGOs), played a role in this decline. The adoption of a ‘100% condom’ policy that enforced condom use in brothels led to a substantial rise in condom use among sex workers and their clients and a drop in HIV infection levels among brothel-based sex workers. However, ongoing concerns include low levels of condom use among MSM, an increase in sex work occurring outside of brothels (making it harder to reach sex workers with interventions), and mother-to-child transmission of HIV – around one third of new infections occur through this route. HIV is mostly transmitted through heterosexual sex in Cambodia, and concerns are growing about the number of married women who are infected through their husband.3

HIV prevention and Antiretroviral treatment in Asia

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HIV prevention in Asia

HIV prevention 
sign, Ho Chi Minh City, Vietnam
HIV prevention sign in Ho Chi Minh City, Vietnam
Asia has been the base for some extremely successful large-scale HIV prevention programmes. Well-funded, politically supported campaigns in Thailand and Cambodia have led to significant declines in HIV-infection levels, and HIV prevention aimed at sex workers and their clients has played a large role in these achievements. In Tamil Nadu, India, HIV prevention initiatives have had a substantial impact.

How is HIV transmitted in Asia?

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 In the early to mid-1980s, while other parts of the world were beginning to deal with serious HIV and AIDS epidemics, Asia remained relatively unaffected. By the early 1990s, however, AIDS epidemics had emerged in several Asian countries, and by the end of the decade, HIV was spreading rapidly in many areas of the continent.

Activists 
campaigning against HIV-related discrimination in India
Activists campaigning against HIV-related discrimination in India
Today, around 4.7 million people are living with HIV in Asia.1 Although national HIV prevalence rates in Asia appear to be relatively low, the populations of some Asian countries are so vast that these low percentages actually represent very large numbers of people living with HIV. India, for example, has an estimated HIV prevalence of 0.3%, which seems low when compared to prevalence rates in some parts of sub-Saharan Africa. However, with a population of around one billion, this actually equates to 2.5 million people living with HIV in India.2

Am I ready for sex?

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Almost everyone asks themselves "am I ready to have sex?" at some point in their lives, but unfortunately not many people will be able to answer it with a definite "yes" or "no".

Having sex for the first time can be a very special experience, but it can also lead to all sorts of complications. Sex without a condom or other form of contraception can result in pregnancy, and if your partner has HIV or a sexually transmitted infection (and you might not always know they do), you can become infected too. There can also be emotional consequences to having sex with someone – it can really change a relationship, and not always for the better. Sex can be enjoyable with the right person, but it’s very easy to make mistakes and end up hurt, which is why people advise you: "don’t have sex until you’re ready!"
Of course it's all very well saying this, but how do you know when you’re ready? Legally, you aren’t allowed to have sex with anyone until you’re over the age of consent. But it takes more than just being a legal age to make you ready for sex – you need to be emotionally ready too. Here are some questions to help you work out if you're ready to have sex.

The history of HIV and AIDS in America

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The history of AIDS in America began in 1981, when the United States became the first country to officially recognise a strange new illness among a small number of gay men. Today, it is generally accepted that the origin of AIDS probably lies in Africa. However, America was the first country to bring AIDS into the public consciousness and the American reaction undoubtedly contributed to the establishment of AIDS as one of the most politicised, feared and controversial diseases in the history of modern medicine - a reputation that stands today.

The history of AIDS in America in the 1980s

picture of the 
National AIDS Memorial Grove in San Francisco
The Circle of Friends in the National

HIV and AIDS in the Caribbean

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In 2008 an estimated 20,000 people in the Caribbean became infected with HIV, and around 12,000 died of AIDS. After sub-Saharan Africa, the Caribbean has a higher HIV prevalence than any other area of the world, with 1.0% of the adult population infected.1

An overview of AIDS in the Caribbean

Due largely to their close geographic locations, the Caribbean is usually grouped with Latin America in discussions about HIV and AIDS, but the epidemics in these regions are very different. Even within the Caribbean, each country faces a unique situation. The diversity of the region – which is apparent in terms of politics, languages spoken, geographic location and wealth – is reflected in the significantly different ways that countries are affected.
At one extreme, the Bahamas has the highest HIV prevalence in the entire western hemisphere (3%); at the other, Cuba has one of the lowest (0.1%). Trinidad and Tobago (1.5%) and Jamaica (1.6%) are heavily affected, while Puerto Rico is the only Caribbean country apart from Cuba where it is thought that less than 1% of the population is living with HIV.2 Other factors, such as AIDS mortality rates and transmission patterns, also vary across countries and areas. See our Caribbean statistics page for more data.
Before Haiti's devastating earthquake in January 2010, an estimated 2.2 percent of the population were living with HIV. Haiti's AIDS epidemic is one of the most severe in the Caribbean. Before the earthquake an estimated 126,800 people under the age of 49 were living with the virus, which included 6,800 children; and an estimated 19,000 people were receiving antiretroviral drugs (ARVs). Since the earthquake, thousands of people will still be in need of ARVs, and the priority for AIDS organisations is to get the medication to those in need. It is also critical that HIV prevention, treatment, care and support services are resumed.3
“Haiti's AIDS epidemic is one of the most severe in the Caribbean”

HIV & AIDS in Latin America

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At the end of 2008 there were around 2 million people living with HIV in Latin America - more than in the U.S., Canada, Japan and the UK combined.1 While this region has often been overlooked in the past, there is now growing recognition amongst the international community that the HIV epidemics of Latin American countries demand more attention than they have received so far.
Latin American countries have been affected by HIV and AIDS in different ways, and to different extents. Responses have varied, with some countries displaying weak political leadership and others – most notably Brazil – forming strong and positive responses. Despite many differences between the epidemics of individual countries, high levels of poverty, migration, homophobia and HIV-related discrimination are apparent throughout the region, and these factors present common barriers to overcoming the crisis.2
In this page, we use the term Latin America to refer to the countries of South and Central America, excluding Suriname, Guyana, French Guyana and the Caribbean islands, which we discuss in our HIV & AIDS in the Caribbean page. AVERT.org also has an individual country page about AIDS in Brazil.

HIV & AIDS in Brazil

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The first case of AIDS was recorded in Brazil in 1982, and whilst many countries have struggled to curb the spread of HIV and to care for those with AIDS, Brazil’s response has been seen as a success story. Working alongside civil society groups, the Brazilian government has made aggressive efforts to minimise the impact of the AIDS epidemic. By the end of 2007, 730,000 Brazilians were living with HIV1 – just over half the number that estimates in the previous decade had predicted.2 The AIDS mortality rate has fallen and the number of people who avoided hospital due to to effective treatment saved over US$2 billion in medical costs between 1996 and 2004.3
To understand Brazil’s achievements, the historical context in which they took place must first be acknowledged.

The history of AIDS in Brazil

Although it was first declared a republic in 1889, Brazil spent most of the following century under a series of military dictatorships. It was under the last of these dictatorships, at a time when citizen groups and non-governmental organisations (NGOs) were expanding and becoming more outspoken in their calls for change, that the country’s first AIDS case was recorded in 1982. 4 Although relatively few cases of HIV were recorded over the next few years, these civil society groups made sure that the government was quick to act and did not ignore the problem. As the country moved closer to democracy, they encouraged a climate of social solidarity, allowing open and frank debate about HIV and AIDS.

HIV and AIDS in America

Tuesday 8 June 2010 · 0 comments

Since the beginning of the HIV and AIDS epidemic well over half a million people have died of AIDS in America1  – the equivalent of the entire population of Las Vegas. There are currently more than one million people living with HIV and AIDS in America and around a fifth of these are unaware of their infection,2 posing a high risk of onward transmission.
America’s response to the AIDS epidemic has produced mixed results. HIV prevention efforts have not always been successful and every year approximately 56,000 Americans are infected with HIV.3 In March 2009 Washington DC reported an HIV prevalence of at least 3% among people over 12 years - similar to rates in some parts of sub-Saharan Africa.4
Stigma and discrimination towards HIV positive people still persist and thousands of uninsured Americans struggle to access good HIV care and antiretroviral therapy. The world’s biggest donor of AIDS-related funding is itself facing a major, ongoing AIDS epidemic, which shows little sign of abating.

Who is affected by AIDS in America?

Although HIV and AIDS can and do affect all sectors of American society, the impact has been more serious among some groups than others. In the early years of the epidemic, the most commonly identified ‘vulnerable groups’ in America were men who have sex with men, injecting drug users, haemophiliacs and Haitians. Today, AIDS continues to directly affect thousands of gay and bisexual men and injecting drug users every year, but it has also become a serious problem among Black Americans and, more recently, among the Hispanic/Latino population.

The impact of HIV & AIDS in Africa

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Two-thirds of all people infected with HIV live in sub-Saharan Africa, although this region contains little more than 10% of the world’s population.1 AIDS has caused immense human suffering in the continent. The most obvious effect of this crisis has been illness and death, but the impact of the epidemic has certainly not been confined to the health sector; households, schools, workplaces and economies have also been badly affected.
During 2008 alone, an estimated 1.4 million adults and children died as a result of AIDS in sub-Saharan Africa.2 Since the beginning of the epidemic more than 15 million Africans have died from AIDS.3
Although access to antiretroviral treatment is starting to lessen the toll of AIDS, fewer than half of Africans who need treatment are receiving it.4 The impact of AIDS will remain severe for many years to come.

The impact on the health sector

In all heavily affected countries the AIDS epidemic is adding additional pressure on the health sector. As the epidemic matures, the demand for care for those living with HIV rises, as does the toll of AIDS on health workers. In sub-Saharan Africa, the direct medical costs of AIDS (excluding antiretroviral therapy) have been estimated at about US$30 per year for every person infected, at a time when overall public health spending is less than US$10 per year for most African countries.5

The effect on hospitals

Kisiizi Hospital's
 bedroom
Nurses working on the HIV ward at Kisiizi Hospital in Uganda

AIDS in Africa summary

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Sub-Saharan Africa is more heavily affected by HIV and AIDS than any other region of the world. An estimated 22.4 million people are living with HIV in the region - around two thirds of the global total. In 2008 around 1.4 million people died from AIDS in sub-Saharan Africa and 1.9 million people became infected with HIV. Since the beginning of the epidemic more than 14 million children have lost one or both parents to AIDS.1

In the absence of massively expanded prevention, treatment and care efforts, it is expected that the AIDS death toll in sub-Saharan Africa will continue to rise. This means the impact of the AIDS epidemic on these societies will be felt most strongly in the course of the next ten years and beyond. Its social and economic consequences are already widely felt, not only in the health sector but also in education, industry, agriculture, transport, human resources and the economy in general. The AIDS epidemic in sub-Saharan Africa threatens to devastate whole communities, rolling back decades of development progress.
Sub-Saharan Africa faces a triple challenge:
  • Providing health care, antiretroviral treatment, and support to a growing population of people with HIV-related illnesses.
  • Reducing the annual toll of new HIV infections by enabling individuals to protect themselves and others.
  • Coping with the impact of over 20 million AIDS deaths, on orphans and other survivors, communities, and national development.

The 1990s – Southern Africa and the Fight for Treatment

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The beginning half of the 1990s was a bleak time in the history of AIDS in Africa. At a time when new HIV infection rates were rocketing in Southern Africa there were few new ideas of how to deal with generalised epidemics in poor countries1. Prevention campaigns were having minimal effect and there was no visible prospect for effective treatment in Africa. The international community was yet to take efficient action and many national government programmes were corrupt or ill-equipped to deal with the escalating crisis2. By the middle of the decade the seriousness of the epidemic was blatant. In 1999, the Kenyan President Daniel Arap Moi declared AIDS a national disaster.

"AIDS is not just a serious threat to our social and economic development, it is a real threat to our very existence, and every effort must be made to bring the problem under control." 3
Although HIV/AIDS prevalence continued to increase in Southern Africa in the later Nineties, glimmers of hope for the future of the epidemic began to emerge.
Prevalence rates in many East African countries that were hard hit in the 1980s were beginning to slow, stabilise or decline. Between 1992 and 1998 prevalence rates in Uganda were estimated to have dropped from 30% to 12% of adults in Kampala4.
In 1996, UNAIDS was established to take responsibility for coordinating international action against the epidemic5 6.

AIDS in Africa has had a short but devastating history.

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“It all started as a rumour…  Then we found we were dealing with a disease.  Then we realised that it was an epidemic.  And, now we have accepted it as a tragedy.” - Chief epidemiologist in Kampala, Uganda1

Adult HIV prevalence (%) in Africa between 1988 and 2003

Maps of the spread of HIV in Africa between 1988 and 2003
  • 20%-30%
  • 10%-20%
  • 5%-10%
  • 1%-5%
  • 0%-1%
  • data unavailable

Before the 1960s – African origins of AIDS

Introduction to the global AIDS epidemic

Monday 7 June 2010 · 0 comments

The start of AIDS

The history of AIDS is a short one. As recently as the 1970s, no one was aware of this deadly illness. Since then the global AIDS epidemic has become one of the greatest threats to human health and development. At the same time, much has been learnt about the science of AIDS, as well as how to prevent and treat the disease.

The global picture

Statistics for the end of 2008 indicate that around 33 million people are living with HIV, the virus that causes AIDS. Each year around 2.7 million more people become infected with HIV and 2 million die of AIDS.1
Although HIV and AIDS are found in all parts of the world,

World AIDS Day 2009

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World AIDS Day theme: Universal Access and Human Rights

The theme for World AIDS Day 2010 is 'Universal Access and Human Rights'. Global leaders have pledged to work towards universal access to HIV and AIDS treatment, prevention and care, recognising these as fundamental human rights. Valuable progress has been made in increasing access to HIV and AIDS services, yet greater commitment is needed around the world if the goal of universal access is to be achieved. Millions of people continue to be infected with HIV every year. In low- and middle-income countries, less than half of those in need of antiretroviral therapy are receiving it, and too many do not have access to adequate care services.3
The protection of human rights is fundamental to combating the global HIV and AIDS epidemic. Violations against human rights fuel the spread of HIV, putting marginalised groups, such as injecting drug users and sex workers, at a higher risk of HIV infection. By promoting individual human rights, new infections can be prevented and people who have HIV can live free from discrimination.
World AIDS Day provides an opportunity for all of us - individuals, communities and political leaders - to take action and ensure that human rights are protected and global targets for HIV/AIDS prevention, treatment and care are met.

HIV structure and life cycle

Sunday 6 June 2010 · 0 comments

HIV stands for Human Immunodeficiency Virus. Like all viruses, HIV cannot grow or reproduce on its own. In order to make new copies of itself it must infect the cells of a living organism.

The Structure of HIV

What does HIV look like?

HIV and CD4+ cell In this computer generated image, the large object is a
human CD4+ white blood cell, and the spots on its surface
and the spiky blue objects in the foreground
represent HIV particles.
Outside of a human cell, HIV exists as roughly spherical particles (sometimes called virions). The surface of each particle is studded with lots of little spikes.
An HIV particle is around 100-150 billionths of a metre in diameter. That's about the same as:
  • 0.1 microns
  • 4 millionths of an inch
  • one twentieth of the length of an E. coli bacterium
  • one seventieth of the diameter of a human CD4+ white blood cell.

Origins of HIV and AIDS

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The origin of AIDS and HIV has puzzled scientists ever since the illness first came to light in the early 1980s. For over twenty years it has been the subject of fierce debate and the cause of countless arguments, with everything from a promiscuous flight attendant to a suspect vaccine programme being blamed. So what is the truth? Just where did AIDS come from?

The first recognised cases of AIDS occurred in the USA in the early 1980s (more about this period can be found on our History of AIDS page). A number of gay men in New York and California suddenly began to develop rare opportunistic infections and cancers that seemed stubbornly resistant to any treatment. At this time, AIDS did not yet have a name, but it quickly became obvious that all the men were suffering from a common syndrome.
The discovery of HIV, the Human Immunodeficiency Virus, was made soon after. While some were initially resistant to acknowledge the connection (and indeed some remain so today), there is now clear evidence to prove that HIV causes AIDS. So, in order to find the source of AIDS, it is necessary to look for the origin of HIV, and find out how, when and where HIV first began to cause disease in humans.

How?

HIV testing in pregnancy

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In many countries across the world, women are tested for HIV during pregnancy. There are a number of important reasons for this:

  • HIV infection can be passed on to a baby during pregnancy, labour and delivery, and breastfeeding. With appropriate treatment and intervention, the chances of a child becoming infected can be reduced from around 25% to less than 2%. It is therefore vital that an HIV infection in a mother is identified during the early stages of pregnancy to allow for an opportunity to reduce the risk of transmission to the baby. AVERT.org has more information about mother-to-child transmission (MTCT), including details of a Stop AIDS in Children campaign, which is calling for better prevention of MTCT around the world.
  • In areas where antiretroviral therapy is available, a pregnant woman can receive these drugs if she tests HIV positive during pregnancy. The antiretroviral drugs can suppress HIV, which will keep her healthy for longer.
  • For many women, especially in resource-poor areas, pregnancy will be the only time in their young adult lives when they access healthcare services on a regular basis. It therefore presents an excellent opportunity not only to screen for HIV, but also to educate and advise about the dangers of the virus.

Routine, voluntary HIV testing

In most developed nations, HIV tests are either routinely offered as part of antenatal care or are offered to pregnant women thought to be at high risk of exposure to HIV. This has helped to reduce rates of mother-to-child transmission dramatically.1 There are two types of routine testing: opt-out and opt-in.

HIV testing

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The different types of HIV test

Using a rapid oral
 HIV test
Using a rapid oral HIV test

HIV antibody test

HIV antibody tests are the most appropriate test for routine diagnosis of HIV among adults.  Antibody tests are inexpensive and very accurate. The ELISA antibody test (enzyme-linked immunoabsorbent) also known as EIA (enzyme immunoassay) was the first HIV test to be widely used.

How do antibody tests work?

When a person is infected with HIV, their body responds by producing special proteins that fight infection, called antibodies. An HIV antibody test looks for these antibodies in blood, saliva or urine. If antibodies to HIV are detected, it means a person has been infected with HIV. There are only two exceptions to this rule:

What Is HIV ?

- Whether you're new to HIV or already an expert, there is always more to know.
- In fact, there's so much to learn about HIV that it can seem overwhelming.
- But that's what we're here for.
- Use this page as a starting point for learning everything you need to know about HIV.
....